Competitive, competitive, competitive.
Pervasive sense of elitism and excessive pride.
Some established practices are too fixed and accepted without questioning or challenging them (no matter how outdated they may be). People are generally not as receptive to new ideas or "other" opinions apart from a few usual vocal suspects.
Some groups have inexperienced and much to be desired mid-level managers.
Headstrong junior scientists with false pretense of power.
Unrealistic demand for workload. No work/life balance.