Pros
The Institute has an excellent mission, to create tools to assist neurological research around the world and make the tools and data available as public domain. They provide excellent benefits, including medical and dental without any employee premiums and low copays. The people working at AIBS are by and large intelligent, hard working and excellent people to work with.
Cons
The Allen Institute for Brain Science is a small company trying to grow, and going through some growing pains. They have ambitious short term goals combined with poor planning by project leads, which creates unmanageable deadlines for people downstream. Upper management and PhD's sometimes ignore advice of those working in "lower" positions without advanced degrees, regardless of experience.